Kratom, derived from the leaves of the Mitragyna speciosa tree, is commonly used in the U.S. for pain relief, energy, and mood support. Past-year use affects ~0.7–0.8% of adults (~2 million), often for pain management or opioid withdrawal. Available in forms like powders, capsules, and tea, its effects vary by dose and individual metabolism.
Regular or high-dose use can lead to dependence, with ~25–67% of regular users meeting DSM-5 criteria for Kratom Use Disorder, primarily mild and involving tolerance or withdrawal. While effects typically last a few hours, knowing the duration helps ensure safe use and prepare for withdrawal or detox if needed.