Crank is a colloquial term referring to methamphetamine, a potent synthetic stimulant with significant abuse potential and a substantial public health impact across the United States. Current epidemiological data indicate that more than 2.6 million Americans aged 12 and older reported methamphetamine use within the past year, reflecting the magnitude of this clinical and social concern.
Understanding the terminology associated with methamphetamine—including street names and slang references—is essential for healthcare providers, families, and communities seeking to identify early signs of use and initiate appropriate intervention pathways. This article provides a comprehensive overview of crank’s definition, routes of administration, acute and chronic physiological effects, epidemiological trends, mechanisms of dependence, and evidence-based treatment modalities available through specialized addiction treatment programs.





