Doctors often prescribe antidepressants like Wellbutrin and Prozac to treat conditions such as depression and anxiety. A meta-analysis of 7 randomized trials with 1,463 patients found them equally effective: response rates of 62% for Wellbutrin and 63% for SSRIs like Prozac, with 47% remission for both. They’re both effective, but they don’t work the same way in your brain – one might boost your energy, while the other focuses more on lifting your mood.
Figuring out the differences can help you and your doctor pick what’s best for you. If you’re trying to decide between Wellbutrin vs. Prozac, we’ll break down how they work, what they’re used for, their side effects, and the risks involved so you can make a smarter choice.





