Topiramate, often prescribed under the brand name Topamax, is commonly used to treat seizures and prevent migraines. For many patients, it plays an important role in stabilizing neurological conditions. But like many medications that influence brain chemistry, it can be misused. Although Topiramate is not classified as a controlled substance, dependency can still develop.
A PMC study found 24% psychiatric adverse events (including 10.7% affective disorders) in epilepsy patients on topiramate, with higher dropout rates due to cognitive effects (12-23% in migraine trials). Some people begin increasing doses without guidance. Others misuse it for appetite suppression or emotional relief. Over time, patterns like these can lead to physical complications and psychological reliance. Understanding how Topiramate works and recognizing early warning signs of misuse can help prevent long term harm.
