Xanax and Alcohol: Side Effects and Risks

Medical Providers:
Dr. Michael Vines, MD
Alex Spritzer, FNP, CARN-AP, PMHNP
Clinical Providers:
Natalie Foster, LPC-S, MS
Last Updated: January 26, 2026

Xanax and Alcohol

People often assume that a prescription medication and a few drinks won’t cause serious harm. We see the opposite happen far too often. Xanax and alcohol both slow the central nervous system, and when they overlap, the body can lose its ability to regulate breathing and awareness.

The NIDA reported that benzodiazepines were involved in 10,870 overdose deaths in the U.S. in 2022, with alcohol present in many cases. According to CDC overdose surveillance data, benzodiazepines are frequently involved in fatal overdoses, especially when combined with other central nervous system depressants such as alcohol. Even when neither substance feels excessive, the combination can become dangerous quickly.

Our Xanax Addiction Treatment Centers

Learn the best practices for managing Xanax and alcohol.

What is Xanax?

Xanax, also called alprazolam, is a prescription benzodiazepine most often used to treat anxiety and panic attacks. It is known for working fast, which is one reason it is commonly prescribed and also why it carries risk.

The medication increases the activity of GABA, a chemical in the brain that slows nerve signals. For someone in acute anxiety, this can feel like relief. For others, especially with repeated use, it can lead to sedation, slowed reflexes, and dependence. Because Xanax acts quickly and wears off relatively fast, some people take it more often than intended, which increases the chance of misuse and unsafe combinations.

xanax and alcohol

What is Alcohol?

Alcohol is a psychoactive substance found in beer, wine, and spirits. It is widely used and socially accepted, which often masks how strongly it affects the brain and body.

Alcohol slows communication between brain cells. In lower amounts, people may feel relaxed or less inhibited. As intake increases, coordination drops, judgment becomes unreliable, and reaction time slows. At higher levels, alcohol can interfere with breathing and consciousness. When alcohol is combined with medications that have similar effects, those risks increase rather than balance out.

What Happens if You Mix Xanax and Alcohol?

When Xanax and alcohol are taken together, the brain receives overlapping signals to slow down. Breathing, alertness, and protective reflexes can all be affected.

This is not a rare interaction. Even moderate drinking combined with a prescribed dose of Xanax can lead to excessive sedation, confusion, or blackouts. Many people who experience benzodiazepine-related overdoses report that alcohol was involved, even when neither substance felt dangerous on its own.

Because the body cannot easily compensate for both substances at once, medical providers consistently advise against mixing them.

Dangers of Mixing Xanax and Alcohol

Xanax and alcohol intensify each other’s effects. From a treatment standpoint, this combination is one of the most common contributors to emergency situations involving benzodiazepines.

The risks include:

  • Depressing the Nervous System: Together, these substances can slow breathing and heart rate more than expected. In some cases, people become unresponsive or lose consciousness without warning.
  • Messing with Your Thinking: Judgment, coordination, and reaction time decline sharply. This increases the likelihood of falls, car accidents, and risky decisions that wouldn’t otherwise happen.
  • Risking Overdose: Both Xanax and alcohol suppress breathing. When combined, the risk of respiratory failure rises, even at doses that seem familiar.
  • Forgetting Stuff: Memory gaps and blackouts are common. People may not remember conversations, actions, or entire periods of time, which can lead to unsafe situations or lasting consequences.
  • Worsening Mental Health: Over time, mixing Xanax and alcohol can intensify anxiety and mood issues. Some people notice more panic, irritability, or depressive symptoms as brain chemistry becomes disrupted.

Begin your recovery today with personalized treatment at The Hope House

What Are the Side Effects of Alcohol and Xanax?

Side effects from mixing alcohol and Xanax are often stronger and less predictable than expected. They can appear suddenly and escalate quickly.

  • Extreme Drowsiness: People may feel unable to stay awake or alert. Tasks like driving or working become unsafe.
  • Messing with Coordination: Balance and motor control are impaired. Falls and injuries are more likely.
  • Feeling Dizzy and Light-headed: Light-headedness or a spinning sensation can occur, especially when standing or moving quickly.
  • Fuzzy Thinking: Concentration drops. Memory becomes unreliable. Many people describe feeling mentally “checked out.”
  • Upset Stomach: Nausea and vomiting may occur as alcohol irritates the stomach while Xanax affects the nervous system.

Withdrawal From Xanax and Alcohol

Stopping Xanax and alcohol can be physically and emotionally difficult, particularly when both have been used regularly. Anxiety, sleep disruption, tremors, and agitation are common. In more severe cases, seizures can occur.

Benzodiazepine withdrawal should never be managed alone. Alcohol withdrawal also carries medical risks. Supervised care allows symptoms to be monitored and treated safely, reducing the chance of complications.

Xanax and Alcohol Rehab Near Me

If Xanax and alcohol use has started to feel unmanageable, help is available. At The Hope House, we work with individuals who want a safer, more stable path forward.

Our programs in Scottsdale, Arizona are built around personalized treatment. Treatment may include medication-assisted treatment, trauma-informed care, and dedicated support from our team, depending on each person’s needs. We focus on long-term stability, not just short-term symptom control.

Taking the first step can feel intimidating, but it often brings relief. We are here to explore treatment options with you safely.

xanax and alcohol

Other Drugs Commonly Mixed with Alcohol

Mixing Lexapro and alcohol is generally not recommended due to several reasons. Combining these substances can increase sedation and lead to excessive drowsiness, dizziness, and impaired coordination.

The mixture of Adderall and alcohol has gained attention due to the increasing prevalence of prescription stimulant use and alcohol consumption among various age groups. Unfortunately, some individuals may be unaware of the harmful consequences that can arise from this risky combination.

Opioids and alcohol, are two substances that, when misused, can pose serious risks to one’s health and well-being. The dangerous combination of alcohol and opioids has become a significant concern in public health due to the potential for harmful interactions.

Zoloft and alcohol both slow down the brain as they’re both considered depressants for the central nervous system. Using them together increases the chances of feeling more sleepy, dizzy, and having trouble coordinating, which raises the risk of accidents or injuries.

Discovering the risks of using Prozac and alcohol together is essential for your well-being. Let’s explore the potential dangers and interactions you should know about when combining Prozac and alcohol.