Gamma hydroxybutyrate (GHB) is a powerful central nervous system depressant commonly known as a club drug or the “date rape drug” due to its association with sexual assault cases. It is often used recreationally for its sedative and euphoric effects. According to the National Survey on Drug Use and Health, an estimated 1.2 million people in the United States have reported using GHB, with rates reaching 12% among regular ecstasy and stimulant users. GHB is a highly addictive substance that can have severe effects on both physical and mental health.
GHB moves through the body quickly, with a half-life of just 30 minutes to one hour in most adults. This short window is one reason it’s so dangerous—people often underestimate how unpredictable it can be, especially when doses are repeated or mixed with alcohol. The effects typically last three to four hours, but higher doses can extend them to six hours or longer. Understanding how long GHB stays in your system is crucial for effective addiction treatment, clarifying drug testing results, and making safer decisions moving forward.